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Drug Development

Streamline your drug development process

BreakSight® empowers drug development by providing advanced insights into DNA damage mechanisms and their therapeutic implications. Accelerate the identification of novel biomarkers and enable a deeper understanding of drug efficacy, safety, and resistance mechanisms.

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Why BreakSight?

Equip researchers with data to develop effective therapies

Identify DNA damage patterns in cells exposed to your drug compound

BreakSight® pinpoints recurring DNA break sites in cells that are sensitized to specific treatments. These patterns can reveal the basis for mutations or genomic rearrangements driving drug sensitivity or resistance.

Compare treated and resistant states

By comparing DNA break profiles between treated and resistant cells, BreakSight® helps identify the genomic changes that differentiate the two states. This can uncover new resistance mechanismsand targets.

Profile genomic effects of drug combinations

BreakSight® evaluates DNA damage from individual drugs and their combinations, revealing additive effects on DNA breakage.

Highlight complementary mechanisms

Understanding DNA damage synergy helps researchers fine-tune dosages and schedules to maximize therapeutic benefits while minimizing off-target effects.

Gain a deeper understanding of drug induced DNA damage

BreakSight® equips researchers with the data needed to develop more effective therapies, characterize potential mechanisms of resistance, and harness the full potential of combination treatments, all at the genomic level.

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Illustration of a human cell with three circular areas highlighted, representing specific structures or focal points within the cell.